Mark Flaw On The Marker Tool
This option enables you to define a part of the marker table as a flaw area (a bad area of the cloth that needs to be ignored while nesting).
Icon & Location
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                                            Menu: Marker>Flaws>Mark Flaw on the Marker 
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                                            Toolbar: Marker Tool 
To use the Mark Flaw On The Marker tool:
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                                            From the main menu, go to Marker > Flaws > Mark Flaw on the Marker. 
 The mouse turns into a rectangle tool.
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                                            Draw a rectangle on the marker that defines the flaw area:  
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                                            When you are done drawing the rectangle left click with your mouse and release. 
 The Flaw dialog appears: 
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                                            You can now manually define the flaw limit for Left/Right/Top/Bottom. 
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                                            Click Whole Length Flaw, if you want the flaw to be on the entire length of the fabric.  
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                                            Click Whole Width Flaw, if you want the flaw to be on the entire width of the fabric:  
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                                            Click Ok when you are done. 
 Now once you nest, the marked area will be ignored.